An independent peptide review
Clear-eyed guidance on peptides for sleep, recovery, and healthy aging.
We read the primary research so you don't have to — separating the mechanism that holds up from the marketing that doesn't. No hype, every claim sourced, editorially independent.
Our #1 ranked provider
CoreAge Rx
$99/ month, flat
Doctor-reviewed sermorelin from a 503A compounding pharmacy, with nurse and dietitian consults included — one number that does not climb with your dose.
- Pharmacy
- 503A compounding
- Oversight
- Doctor-reviewed
- Support
- Nurse + dietitian
- Labs
- Not required
Affiliate partner — we earn a commission if you start here, at no extra cost to you. Worth knowing either way: sermorelin raises growth hormone, but the sleep-outcome evidence in healthy adults is thin, and we say so in the evidence review. Disclosure
The evidence
What the research actually shows
Sermorelin for Sleep, Recovery & Healthy Aging
What sermorelin is, the GHRH–sleep mechanism, and where the clinical record is thin.
Read the review- Sleep
Does Sermorelin Improve Deep Sleep?
GHRH boosts slow-wave sleep in research settings — but the effect fades with age.
Read - Body composition
Does Sermorelin Build Muscle or Burn Fat?
The best-matched human trial raised GH but showed no muscle or fat-loss benefit.
Read - Longevity
Is Sermorelin Really 'Anti-Aging'?
Separating the durable physiology from the borrowed and overstated anti-aging claims.
Read - Research
Tesamorelin vs Sermorelin: How They Actually Differ
Tesamorelin is FDA-approved for HIV visceral fat; sermorelin is compounded and off-label. Same GHRH mechanism, very different evidence — an honest comparison.
Read - Research
Sermorelin vs Ipamorelin: Evidence Compared
Sermorelin is a compounded GHRH analog; ipamorelin a ghrelin-receptor secretagogue. Different receptors, different evidence — an honest comparison.
Read - Research
Oral & Sublingual Sermorelin: Does It Actually Work?
Oral and sublingual sermorelin are sold as needle-free options, but peptide absorption is brutally poor. The honest pharmacology and the real GHRH route data.
Read - Research
Sermorelin Before & After: What to Realistically Expect
No dramatic transformation photos here — just what the evidence actually supports, a realistic week-by-week timeline, and where the marketing overreaches.
Read - Research
Does Sermorelin Cause Cancer? What the Evidence Says
Sermorelin raises GH and IGF-1, and IGF-1 is linked to some cancers. No trial shows sermorelin causes cancer — but the unknowns and contraindications are real.
Read - Research
Sermorelin Dosing: What the Research Actually Supports
What the trials actually show on sermorelin doses: 1 mcg/kg diagnostic, 30 mcg/kg/day in children. There is no validated adult anti-aging dose.
Read
Evidence-based
Every conclusion traces back to primary research or official drug labeling.
Every claim sourced
Inline citations to the studies — including the null results and age caveats.
Editorially independent
Rankings reflect evidence and judgment, never the size of a commission.
Edited by Adrian Cole, Lead Research Editor. Read how we research and rank in our editorial policy.